FIELD: medicine, pharmaceutics.
SUBSTANCE: what is presented is application of an effective amount of the composition containing nanoparticles containing taxane and a carrier protein for preparing a drug for a proliferative disease in a combination with an effective amount of at least one other chemotherapeutic agent specified in a group consisting of antimetabolite, platinum agents, alkylating agents, tyrosine kinase inhibitors, anthracycline antibiotics, vinca alkaloids, proteasome inhibitors, macrolides, a therapeutic antibody, an antiangiogenic agent, geldanamycin, 17-AAG and topoisomerase inhibitors; a related composition and a kit.
EFFECT: shown higher clinical effectiveness in combined treatment of even hard-to-treat cancers, including cancer of lungs and pancreatic cancer with no new toxicity cases detected.
46 cl, 9 dwg, 16 ex
