FIELD: medicine.
SUBSTANCE: group of inventions relates to the treatment of cancer. A nanoparticle complex for the treatment of cancer contains albumin, 20-acetoxy-4-deacetyl-5-epi-20,O-secotaxol and antibodies with an antigen-binding domain, where antibodies are bound to albumin through non-covalent bonds and are located on the outer surface of the nanoparticle complex, and where 20-acetoxy-4-deactyl-5-epi-20,O-secotaxol is less toxic than paclitaxel. A composition of nanoparticles, a method for destroying cancer cells in a population of cancer cells and a method for treating cancer in a patient in need are also disclosed.
EFFECT: group of inventions provides reduced toxicity.
17 cl, 17 dwg, 2 tbl, 8 ex
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