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2 672 918

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IPC

A61K31/195(2006-01-01)

A61P9/10(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2017137469, 2017-10-25

(24)

Start date

2017-10-25

(22)

Actual filing date

2017-10-25

(45)

Published

2018-11-21

(72)

Inventor

Vasileva Olga SergeevnaMakarenko Sergej ValentinovichOtellin Vladimir AleksandrovichKhozhaj Lyudmila IvanovnaTyurenkov Ivan Nikolaevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Pedagogicheskij Universitet Im. A.I. Gertsena" Im. A.I. Gertsena)Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Fiziologii Im. I.P. Pavlova Rossijskoj Akademii Nauk

AGENT HAVING A PROPERTY TO PREVENT DEATH OF GABA-ERGIC NEURONS IN CONDITIONS OF ACUTE PERINATAL HYPOXIA Russian patent published in 2018 - IPC A61K31/195 A61P9/10 A61P25/00

Abstract RU 2672918 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to the pharmaceutical industry and medicine. Use of 4-amino-3-phenylbutanoic acid hydrochloride of the following structural formula (I) as an agent having the property of preventing the death of GABAergic neurons in conditions of acute perinatal hypoxia is proposed. Low toxicity of the compound provides its long-term use for pharmacological correction of the consequences of CNS damage in children with perinatal hypoxia. structural formula (I).

EFFECT: technical result consists in the expressed property to prevent damage and death of GABAergic neurons in conditions of acute perinatal hypoxia both on the 20^th and on the 40^th day of postnatal development.

1 cl, 3 tbl

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RU 2 672 918 C1

Authors

Vasileva Olga Sergeevna

Makarenko Sergej Valentinovich

Otellin Vladimir Aleksandrovich

Khozhaj Lyudmila Ivanovna

Tyurenkov Ivan Nikolaevich

Dates

2018-11-21—Published

2017-10-25—Filed