SURFACE-REACTED CALCIUM CARBONATE FOR DESENSITIZING TEETH Russian patent published in 2018 - IPC A61K6/00 A61K8/19 A61K33/10 A61Q11/00 

Abstract RU 2674030 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to a new additive for desensitizing hypersensitive teeth, use thereof and compositions based thereon. Surface-reacted calcium carbonate can be used in treating dentine hypersensitivity, wherein the surface-reacted calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and at least one acid. Wherein the acid is selected from the group consisting of hydrochloric acid, sulphuric acid, sulphurous acid, phosphoric acid, citric acid, oxalic acid, acetic acid, formic acid, and mixtures thereof. Carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source. Molar ratio of the at least one acid to the natural or synthetic calcium carbonate is from 0.05 to 4. Oral care composition including such a calcium carbonate can be used in treating dentine hypersensitivity, as well as an oral care composition containing such a calcium carbonate, wherein said calcium carbonate is in the form of particles having a volume top cut particle size (d98), equal to or less than 6 mcm. Due to the surface structure of said calcium carbonate, which is different from the usual calcium carbonate, such surface-reacted calcium carbonate can close the dentinal tubules without cutting off the diffusion nutraceutical flow into the dentinal tubules, and can also remain in the tubules for a long period of time, which allows effectively desensitizing the teeth hypersensitivity. Said surface treatment further converts calcium carbonate to a state that is more resistant to the effects of an acidic environment, in particular, while consuming acidic beverages or acidic foods.

EFFECT: surface-reacted calcium carbonate and/or oral care composition based thereon can be used for professional, out-patient treatment or for home treatment.

18 cl, 8 dwg, 5 ex

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RU 2 674 030 C2

Authors

Gane, Patrick A. C.

Gerard, Daniel E.

Budde, Tanja

Schoelkopf, Joachim

Dates

2018-12-04Published

2015-03-20Filed