FIELD: medicine.
SUBSTANCE: group of inventions relates to immunology, and relates to a combination of chlamydial vaccine. Vaccine consists of a recombinant adenoviral vector based on human fifth-type adenovirus serotype expressing the gene for the full-length structural protein CdsF of the chlamydia type III secretion system, and an emulsion containing recombinant structural protein rCdsF secretion system type III chlamydia and a combined adjuvant. Methods for producing a vaccine and methods for producing recombinant proteins for a combination vaccine is also proposed.
EFFECT: group of inventions provides for the induction of a protective immune response against a chlamydial infection in a subject.
14 cl, 30 dwg, 9 ex
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Authors
Dates
2019-01-11—Published
2016-05-12—Filed