FIELD: medicine.
SUBSTANCE: method of producing a recombinant vaccine provides producing chimeric proteins or DNA expressing genes of these chimeric proteins consisting of three or more functional parts. These parts are active material of the vaccine and presented by a pathogenic microorganism antigen, a TLR-receptor ligand and ligants for receptors transferring signal through ITAM-motives. The chimeric proteins are directly used as vaccines for human and animal immunisation. For the vaccines representing DNA coding the chimeric protein, recombinant adenovirus particles and/or plasmid DNA are used as a carrier.
EFFECT: vaccination accompanying preventive treatment of infectious diseases.
29 dwg, 6 ex
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