COMBINATION THERAPY Russian patent published in 2019 - IPC A61K39/395 A61P35/00 

Abstract RU 2677245 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, namely to oncology, and can be used to treat cancer. According to the invention, these pharmaceutical combination, method, use and pharmaceutical composition are intended for the treatment of cancer and include the introduction of (2-hydroxyethoxy)-amide 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (compound A) and antibodies A, containing the amino acid sequence of the heavy and light chains presented in SEQ ID NO: 1 and SEQ ID NO: 2, respectively.

EFFECT: use of the inventions makes it possible to treat cancer due to the synergistic effect of the combination of compound A and antibody A with respect to cell proliferation.

20 cl, 1 dwg, 3 ex

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RU 2 677 245 C2

Authors

Khuan Sichzhun

Peters Malte

Tsao Chzhu Aleksander

Gansert Dzhennifer Lorrejn

Chang Devid Dong Eun

Beltran Pedro

Dates

2019-01-16Published

2013-03-13Filed