FIELD: pharmacology.
SUBSTANCE: invention is a method for colorectal adenocarcinoma treatment comprising administration of a composition comprising an effective amount of methylenetetrahydrofolate and cetuximab, wherein the method excludes application of 5-FU, its analogs, prodrugs and/or metabolites.
EFFECT: potentiation of cetuximab against tumour growth in the absence of 5-FU, as well as expansion of the arsenal for colorectal adenocarcinoma treatment.
6 cl, 1 ex, 2 tbl, 4 dwg
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