METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE Russian patent published in 2019 - IPC C07F15/00 A61K31/555 A61K41/00 A61P35/00 

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula (I) (I), including pharmaceutically acceptable salts of the compound. In formula (I): M is selected from the group consisting of iron, ruthenium and osmium, X is selected from the group consisting of Cl^-, Pf₆^-, Br^-, Bf₄^-, ClO₄^-, CF₃SO₃^- and SO₄^-2, n=0, 1, 2, 3, 4 or 5, y=1, 2 or 3, z=0, 1 or 2, Lig in each occurrence is independently selected from the group consisting of R¹ is selected from the group consisting of

and u is an integer, each of R^2a, R^2b, R^2c, R^2d, R^2e and R^2f is hydrogen, R^3a, R^3b, R^3c, R^3d, R^3e, R^3f, R^3g, R^3h and R³ⁱ in each occurrence, each is independently selected from the group consisting of hydrogen and C1-6 alkyl, R^4a R^4b and R^4c in each occurrence is hydrogen; or R^4a and R^4b in each occurrence, when they are present on a thiophene ring together with the atom to which they are bound to form an optionally substituted ring having 6 ring atoms containing two oxygen atoms. Number of compounds specified in the claims is excluded. Method for treating, method for destroying pathogens, method for sterilizing and method for using a compound of formula (I) as a diagnostic agent are also provided.

EFFECT: compounds according to the invention can be used as agents for diagnosing, treating or preventing diseases associated with unwanted and/or hyperproliferative cell etiology, including cancer and diseases associated with unwanted and/or hyperproliferative cells.

12 cl, 17 tbl, 47 dwg