FIELD: pharmacology.
SUBSTANCE: invention relates to inhibitors of representatives of Tes and Src protein kinases of general formula 1 
. In formula 1, radicals and groups have the values indicated in the claims. The invention also relates to a pharmaceutical composition containing them and their use for treatment of diseases, disorders or conditions associated with Btk, and also to a method for treatment or prevention of diseases, disorders or conditions associated with Btk, includes introduction of the specified pharmaceutical composition.
EFFECT: increased efficiency of treatment.
19 cl, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| PROTEIN KINASE INHIBITORS | 2013 |
|
RU2679122C2 |
| BIR DOMAIN IAP BINDING COMPOUNDS | 2011 |
|
RU2567544C2 |
| DERIVATIVES OF CARBOXYLIC ACIDS (VARIANTS), PHARMACEUTICAL COMPOSITION AND METHOD FO SELECTIVE BINDING αβ-INTEGRIN IN MAMMAL | 2000 |
|
RU2263109C2 |
| OXADIAZOLE-BASED CHANNEL INHIBITORS WITH TRANSIENT POTENTIAL | 2019 |
|
RU2818244C2 |
| METHOD OF SYNTHESIS OF TRIFLUOROMETHYLMERCAPTAN DERIVATIVES | 1991 |
|
RU2024504C1 |
| DERIVATIVES OF PROPIONIC ACID (VARIANTS), PHARMACEUTICAL COMPOSITION AND METHOD FOR SELECTIVE INHIBITION OF αβ-INTEGRIN BINDING | 2000 |
|
RU2255933C9 |
| SYNERGETIC TREATMENT OF PARKINSONISM | 1995 |
|
RU2176145C2 |
| MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF THEIR APPLICATION | 2019 |
|
RU2797558C2 |
| HETEROCYCLIC COMPOUNDS USED IN TREATING DISEASE | 2019 |
|
RU2818246C2 |
| BENZO-DERIVATIVES WITH SIX-MEMBERED RING AS DPP-4 INHIBITOR AND USE THEREOF | 2015 |
|
RU2702644C2 |
