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2 567 544

(13)

(51)

IPC

C07K5/62(2006-01-01)

A61K38/05(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2012139033/04, 2011-02-11

(24)

Start date

2011-02-11

(22)

Actual filing date

2011-02-11

(45)

Published

2015-11-10

(72)

Inventor

Loran AlenPrul MelaniRoz JannikDenisova IrinaDairi KenzaDzharvis SkottDzhakuit Dzhejms B.

(73)

Holder

Farmasajens Ink.

BIR DOMAIN IAP BINDING COMPOUNDS Russian patent published in 2015 - IPC C07K5/62 A61K38/05 A61P35/00

Abstract RU 2567544 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to compounds of formula 1, where G represents a group (1) , where R⁹ represents an aryl, optionally substituted with C₁-C₃alkoxy or halogen; or (2) a substituded or non-substituted azole or pyrrole ring, condensed with a substituted or non-substituted aryl, heteroaryl, C₅-C₆cycloalkyl or heterocyclyl, or to its pharmaceutically acceptable salts, methods of its obtaining and application in the treatment of proliferative disorders, such as cancer.

EFFECT: obtaining the compounds for the treatment of proliferative disorders, such as cancer.

32 cl, 1 tbl, 91 ex

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RU 2 567 544 C2

Authors

Loran Alen

Prul Melani

Roz Jannik

Denisova Irina

Dairi Kenza

Dzharvis Skott

Dzhakuit Dzhejms B.

Dates

2015-11-10—Published

2011-02-11—Filed