FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, namely to pharmaceutical industry. Compound having the structure of formula (V):
as well as a pharmaceutical composition containing a therapeutically effective amount of compound (V) are proposed.
EFFECT: use of the inventions provides a wider range of agents exhibiting inhibitory action against serine proteases - thrombin and kallikrein.
25 cl, 5 tbl, 37 ex
Title | Year | Author | Number |
---|---|---|---|
MULTI-SUBSTITUTED AROMATIC COMPOUNDS AS THROMBIN INHIBITORS | 2011 |
|
RU2639876C2 |
AZAINDOL DERIVATIVES AS FACTOR Xa INHIBITORS | 2004 |
|
RU2330853C2 |
HETEROCYCLIC AMINES AND THEIR APPLICATION | 2011 |
|
RU2632900C2 |
DERIVATIVES OF BENZIMIDAZOL INHIBITING FACTOR Xa | 2004 |
|
RU2346944C2 |
SUBSTITUTED DERIVATIVES OF 1-OXA-2,8-DIAZASPIRO[4,5]DEC-2-ENE, METHOD FOR PRODUCTION THEREOF AND DRUG HAVING ANALGESIC ACTION | 2002 |
|
RU2296128C2 |
INDOLE-2-CARBOXAMIDES AS INHIBITORS OF FACTOR Xa AND/OR VIIa, MEDICINAL AGENT BASED ON THEREOF AND METHOD FOR THEIR PREPARING | 2002 |
|
RU2299881C2 |
HETEROCYCLIC COMPOUNDS AS POSITIVE MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 2 (MGLU2 RECEPTOR) | 2008 |
|
RU2479577C2 |
HETEROCYCLIC INHIBITORS OF Hh-SYGNAL CASCADE, BASED ON THEM MEDICINAL COMPOSITIONS AND METHOD OF TREATING DISEASES INDUCED BY ABBARANT ACTIVITY OF Hh-SIGNAL SYSTEM | 2007 |
|
RU2364597C1 |
POLYCYCLIC AGENTS FOR TREATING RESPIRATORY SYNCYTIAL VIRAL INFECTIONS | 2004 |
|
RU2422444C2 |
8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | 2008 |
|
RU2512541C2 |
Authors
Dates
2019-02-04—Published
2014-03-17—Filed