METHOD OF PRODUCING A NANOSCALE PHYTOSOME SYSTEM Russian patent published in 2019 - IPC A61K31/352 B82B1/00 A61K36/48 B01D11/02 

Abstract RU 2680809 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to the pharmaceutical industry, in particular to a method for producing phytosomes containing quercetin. Method of obtaining phytosomes containing quercetin, with a particle size of phytosomes of 2–12 nm, involves the extraction of 2 g of soybean seeds with 50 ml of a mixture of chloroform-ethanol, taken in a 1:1 ratio, under the influence of ultrasound at a frequency of 22 kHz for 20 minutes, boiling the obtained extract for 20 minutes, after cooling down, add 50 ml of a 1 % solution of quercetin to the resulting extract in 95 % ethanol and the subsequent separation of the ethanol layer, which is exposed to 44 kHz ultrasound for 20–30 minutes.

EFFECT: above method allows to simplify and speed up the process of obtaining a nanoscale phytosome system containing quercetin with high uniformity in size.

1 cl, 2 dwg

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RU 2 680 809 C2

Authors

Marakhova Anna Igorevna

Kezimana Parfe

Stanishevskij Yaroslav Mikhajlovich

Shvitko Boris Semenovich

Smagulova Dilda

Dates

2019-02-27Published

2016-12-20Filed