POLYPEPTIDE AND IMMUNE MODULATION Russian patent published in 2019 - IPC A61K38/16 A61K39/02 A61K48/00 A61P1/00 A61P37/00 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, particularly to the use of flagburgin Roseburia, and/or a polynucleotide sequence encoding said flagburgene Roseburia, and/or vectors, comprising said polynucleotide sequence and/or a host cell comprising a bacterium comprising said vector and/or a host cell comprising bacteria, containing said polynucleotide sequence to reduce inflammation in an individual. Group of inventions also relates to a pharmaceutical composition for reducing inflammation in an individual containing flagellin Roseburia and a pharmaceutically acceptable excipient, a carrier or a diluent. Invention also describes a nutritional supplement, a food substance, a food product, a dietary supplement, a food additive containing flagellin Roseburia. Also described is a method for preparing a pharmaceutical composition and a nutritional supplement containing flagellin Roseburia.

EFFECT: group of inventions provides preparing an agent possessing anti-inflammatory and therapeutically relevant efficacy.

120 cl, 27 dwg, 1 ex, 18 tbl