FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to the production of recombinant lactaptine analogues, and can be used in medicine. Plasmid DNA pEL1 is engineered to provide synthesis of a recombinant EL1 peptide in mammalian cells, and the recombinant EL1 peptide having a molecular weight of 14.1 kDa is obtained.
EFFECT: invention provides preparing a recombinant anti-tumor EL1 peptide, having high cytotoxic activity relative to human cancer cells.
1 cl, 4 dwg, 4 ex
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| RECOMBINANT PLASMID DNA pFK2 PROVIDING SYNTHESIS OF RECOMBINANT PEPTIDE BEING HUMAN KAPPA CASEIN FRAGMENT ANALOGUE, METHOD FOR PREPARING RECOMBINANT PEPTIDE, AND RECOMBINANT PEPTIDE, HUMAN KAPPA CASEIN FRAGMENT ANALOGUE EXHIBITING APOPTOTIC ACTIVITY IN RELATION TO MALIGNANT CELLS | 2009 |
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