FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to the production of recombinant lactaptine analogues, and can be used in medicine. Plasmid DNA pEL1 is engineered to provide synthesis of a recombinant EL1 peptide in mammalian cells, and the recombinant EL1 peptide having a molecular weight of 14.1 kDa is obtained.
EFFECT: invention provides preparing a recombinant anti-tumor EL1 peptide, having high cytotoxic activity relative to human cancer cells.
1 cl, 4 dwg, 4 ex
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Authors
Dates
2019-03-26—Published
2017-12-01—Filed