NEUTRALISING ANTI-INFLUENZA A ANTIBODIES AND USES THEREOF Russian patent published in 2019 - IPC C07K14/11 C12N15/86 C07K16/00 

Abstract RU 2683498 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry. Described is an isolated antibody or a binding fragment thereof capable of binding to influenza A virus hemagglutinin and neutralising at least one group 1 subtype and at least 1 group 2 subtype of influenza A virus, which comprise HCDR1 with sequence SEQ ID NO: 113, HCDR2 with sequence SEQ ID NO:114, HCDR3 SEQ with sequence ID NO:115, LCDR1 with sequence SEQ ID NO:118, LCDR2 with sequence SEQ ID NO:119 and LCDR3 with sequence SEQ ID NO:120. Uses of said antibody are presented.

EFFECT: invention widens the range of agents that neutralise the influenza A virus.

24 cl, 15 dwg, 13 tbl, 11 ex

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Authors

Bendzhamin Eboni

Kallevaard-Lelaj Nikol

Makoliff Dzhozefin Meri

Palmer-Khill Frensis

Uochter Lesli

Yuan Endi

Chzhu Tsin

Korti Davide

Lantsavekkya Antonio

Guarino Barbara

Demarko Anna

Dates

2019-03-28Published

2014-10-01Filed