FIELD: chemistry.
SUBSTANCE: invention relates to a heterocyclic compound of formulas IIc or IIe, where R1 represents C1-C6alkyl; R2 is hydrogen; R3 is hydrogen; each of R4a and R4b independently represents hydrogen or fluorine; R5a and R5b independently represent hydrogen or C1-C3alkyl; and R6 is hydrogen. Invention also relates to specific compounds and pharmaceutical compositions based on these compounds. (IIc IIe).
EFFECT: technical result: new heterocyclic compounds with IRAK4-inhibiting activity have been obtained.
3 cl, 33 ex, 1 tbl
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Authors
Dates
2019-04-08—Published
2016-08-16—Filed