FIELD: pharmacology.
SUBSTANCE: invention relates to substituted amide compounds of formula pharmaceutical compositions containing such compounds and application of such compounds for lowering plasma lipid levels, such as low density lipoprotein cholesterol (LDL-cholesterol) and triglycerides, and thus, for treatment of diseases exacerbated by high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in mammals, including humans.
EFFECT: increased efficiency of compounds application.
42 cl, 10 dwg, 55 ex
Title | Year | Author | Number |
---|---|---|---|
ISOINDOLINONE INHIBITORS OF MDM2-P53 INTERACTION WITH ANTI-CANCER ACTIVITY | 2016 |
|
RU2797295C1 |
NOVEL COMPOUND OF 2,3,5-SUBSTITUTED THIOPHENE AS A PROTEIN KINASE INHIBITOR | 2017 |
|
RU2724957C2 |
CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DESTRUCTION OF ANDROGEN RECEPTORS AND USE THEREOF | 2020 |
|
RU2825000C2 |
COMPOUNDS OF PYRIDAZINAMIDE AND THEIR USE AS SYNTHETIC SYNECKINASIS INHIBITORS (SYK) | 2013 |
|
RU2627661C2 |
PIPERIDINE DERIVATIVES | 2011 |
|
RU2554353C2 |
PYRAZOLO [3,4-C] PYRIDINES AND METHODS OF APPLICATION THEREOF | 2012 |
|
RU2638116C2 |
6-HETEROCYCLYL-4-MORPHOLINE-4-ILPYRIDINE-2-ONES SUITABLE FOR THE TREATMENT OF CANCER AND DIABETES | 2017 |
|
RU2762968C2 |
SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-7-YL COMPOUNDS AS THE INHIBITORS OF PDE2 | 2015 |
|
RU2659070C9 |
SPLICEOSTATIN ANALOGS | 2013 |
|
RU2618523C2 |
SUBSTITUTED NICOTINIMIDE INHIBITORS OF BTK, THEIR PREPARATION AND USE IN TREATMENT OF CANCER, INFLAMMATION AND AUTOIMMUNE DISEASES | 2014 |
|
RU2677884C2 |
Authors
Dates
2017-05-05—Published
2014-04-03—Filed