EMULSIFIED VACCINE FOR PRODUCING CONCENTRATED IgY IMMUNOGLOBULIN COMPOSITIONS; METHODS AND USE THEREOF Russian patent published in 2019 - IPC A61K39/38 A61K39/395 C07K16/02 A61K47/06 A61K9/107 A61K9/50 A61K9/51 A61P31/12 A61K47/36 B82B1/00 

Abstract RU 2689386 C2

FIELD: veterinary medicine.

SUBSTANCE: group of inventions refers to veterinary science and concerns vaccine compositions. Disclosed are: emulsified vaccine composition for immunization of birds to the virus of pigs reproductive and respiratory syndrome (PRRS), containing: (i) PRRS virus antigens, (ii) light mineral oil Marcol and (iii) a dispersed adjuvant selected from a group consisting of biodegradable polymer particles, microparticles or nanoparticles, which is chitosan, wherein the antigens have a titre higher than DIE50 % 104/ ml, use thereof in preparing a concentrated composition of IgG immunoglulins for treating PRRS; concentrated composition of IgG immunoglulins neutralizing virus causing PRRS, a method for production thereof and use thereof for producing a medicinal agent for treating PRRS.

EFFECT: technical result: high titers of IgY antibodies to PRRS virus, high effectiveness of immunoglobulins IgY, neutralizing PRRS virus, no repeated infections of milk piglets with said virus for 6 months and reducing their mortality.

20 cl, 6 dwg, 2 tbl, 7 ex

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RU 2 689 386 C2

Authors

Lucio Decanini Eduardo

Morales Garzon Jose Andres

Dates

2019-05-28Published

2014-08-22Filed