FIELD: chemistry.
SUBSTANCE: invention relates to polymorphous form of compound N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-yl)-2,2-difluoropropanamide, having formula given below, wherein the polymorphous form is crystalline, having a powder X-ray diffraction pattern (CuKα), containing peaks at 10.601, 11.638, 12.121, 13.021, 13.435, 15.418, 15.760, 17.830, 18.753 and 19.671 ± 0.2 ° 2θ. Invention also relates to another polymorphous form of said compound.
EFFECT: technical result is obtaining novel forms of compound N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14- dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, which can be used in treating or preventing a pathological condition associated with inflammation or oxidative stress.
8 cl, 58 dwg, 17 tbl, 4 ex
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