FIELD: biotechnology.
SUBSTANCE: group of inventions relates to the preparation of bacteriocin microorganisms, particularly to production of nisin, and includes strains - producers of bacteriocin and a method for production thereof. Bacteriocin producers are represented by new strains of bacteria Bacillus safensis VKPM V-12180, Bacillus licheniformis VKPM V-12224, Bacillus pumilus VKPM V-12182 and Bacillus endophyticus VKPM V-12181. Produced bacteriocin nisin has a wide spectrum of antimicrobial action. Method of producing bacteriocin is based on cultivation of strains - producers on nutrient medium, separation of culture liquid, its concentration and isolation of bacteriocin with high antimicrobial activity.
EFFECT: group of inventions enables to obtain bacteriocin nisin with high antimicrobial activity.
5 cl, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| STRAIN STREPTOCOCCUS LACTIS - A PRODUCER OF BACTERIOCINE NISINE | 1994 |
|
RU2061042C1 |
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|
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| STRAIN STREPTOCOCCUS LACTIS - A PRODUCER OF BACTERICINE NISINE | 1994 |
|
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| STRAIN OF BACILLUS LICHENIFORMIS FOR OBTAINING HISTIDINE DECARBOXYLASE | 2012 |
|
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