ARGINASE INHIBITORS AND METHODS OF USE THEREOF Russian patent published in 2019 - IPC A61K31/195 A61K31/69 A61P9/10 A61K31/495 

Abstract RU 2695650 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to a compound selected from: , , , , , , , , , , , , , , , , , , , , , , ,

or a pharmaceutically acceptable salt thereof, to use of said compounds for treating diseases selected from a group consisting of a chronic infectious disease, bacterial infection, parasitic infection, trauma, leprosy, tuberculosis, liver transplantation, cancer, fibrous diseases and their combination, and to a pharmaceutical composition containing the above compounds.

EFFECT: group of inventions provides producing the inhibitors of arginic activity, which can be used for treating the disease in a mammal, wherein the disease is characterized by either unusually high arginic activity, or unusually low levels of nitrogen oxide in the mammalian tissue.

3 cl, 14 dwg, 13 tbl, 173 ex

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RU 2 695 650 C2

Authors

Tomchuk Bryus Edvard

Olson Geri Li

Pottorf Richard Skott

Van Dzhejn

Nallaganchu Bkhaskara Rao

Dates

2019-07-25Published

2011-07-26Filed