FIELD: biotechnology.
SUBSTANCE: described is a combination of the obinutuzumab with a CD22 antibody-drug conjugate, which is anti-CD22-MC-vc-PAB-MMAE, for treating CD20 expressing cancer, wherein the anti-CD22 antibody in said conjugate contains a variable light chain domain of SEQ ID NO: 50 and heavy chain variable domain SEQ ID NO: 51.
EFFECT: invention extends the range of products for treating cancer, primarily a combination therapy for treating cancer types in which CD20 is expressed.
5 cl, 4 dwg, 6 tbl
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Authors
Dates
2019-09-12—Published
2014-04-30—Filed