ANTIBODIES TO ALPHA-SYNUCLEIN AND METHODS OF USING Russian patent published in 2019 - IPC C07K16/18 A61K39/395 A61P25/16

Abstract RU 2697098 C1

FIELD: immunology.

SUBSTANCE: present invention relates to immunology. Antibodies binding with human alpha-synuclein, as well as conjugate of antibody with shuttle module for blood-brain barrier are offered. Besides, a pharmaceutical composition and application of antibodies are considered.

EFFECT: present invention can find further application in therapy of various conditions, in particular synucleinopathy and Parkinson's disease.

8 cl, 16 dwg, 9 tbl, 14 ex

Similar patents RU2697098C1

Title	Year	Author	Number
ANTIBODIES TO ALPHA-SYNUCLEIN AND METHODS OF USING	2014	Britschgi Markus Huber Sylwia Kaluza Klaus Kremer Thomas Mundigl Olaf	RU2718990C1
HUMANIZED ANTIBODIES THAT RECOGNIZE ALPHA-SYNUCLEINE	2012	Saldanha Jose Nijjar Tarlochan S.	RU2743738C2
ANTIBODIES AGAINST TRANSFERRIN RECEPTOR HAVING INDIVIDUALIZED AFFINITY	2016	Dengl, Stefan Zhorzh, Gi Gepfert, Ulrikh Nivener, Jens Shlotauer, Tilman	RU2729416C2
PD1 ANTIBODIES AND THEIR APPLICATION METHODS	2016	Zeeber Stefan Lifke Valeria Fisher Ens Vajzer Barbara Vyunshe Ildiko Plettner Oliver Tsvik Adrian Zhorzh Guj Dengl Stefan Levitski Viktor Klyajn Kristian Kodarri Dik Laura Fenn Sebastyan Bents Jerg	RU2746409C1
MONOCLONAL ANTIBODIES TO ALPHA-SYNUCLEIN FOR PREVENTING TAU-PROTEIN AGGREGATION	2017	Fog, Karina Pedersen, Dzheppe, Falsig	RU2760334C2
ANTIBODIES TO LAG3	2018	Codarri Deak Laura Dengl Stefan Fischer Jens Klein Christian Seeber Stefan Weber Patrick Alexander Aaron Zwick Adrian	RU2778053C2
AGENTS, APPLICATION WAYS AND METHODS FOR TREATING SYNUCLEOPATHY	2016	Kallunki, Pekka Fog, Karina Vesterager, Louise, Buur Bergstrom, Ann-Louise Sotty, Florence Satijn, David Van Den Brink, Edward Parren, Paul Rademaker, Rik Vink, Tom Malik, Ibrahim, John Montezinho, Liliana, Christina, Pereira	RU2765303C2
ANTIBODIES AGAINST ALPHA SYNUCLEIN	2018	Adams, Ralph Downey, Patrick Baker, Terence Seward Tyson, Kerry Louise De Lichtervelde, Lorenzo Lightwood, Daniel John Mcmillan, David James	RU2787039C2
HUMANISED HUMAN CD19 ANTIBODIES AND METHODS FOR USE THEREOF	2016	Zhorzh Gi Messner Ekkekhard Lariver Loran Khaas Aleksandr Kettenberger Gubert Ferrara Koller Klaudia Shlotauer Tilman Molkhoj Mikhel	RU2731156C1
AFUCOSYLATED FIBROBLAST GROWTH FACTOR FGFR2IIIB RECEPTOR	2014	Harding, Thomas Pierce, Kristen Patil, Namrata Brennan, Thomas Hambleton, Julie	RU2740714C2

RU 2 697 098 C1

Authors

Brichgi Markus

Khuber Zilviya

Kalutsa Klaus

Kremer Tomas

Mundigl Olaf

Dates

2019-08-12—Published

2014-11-18—Filed