ORALLY DISINTEGRATING SOLID PHARMACEUTICAL DOSAGE UNIT CONTAINING PARTUS CONTROL SUBSTANCE Russian patent published in 2019 - IPC A61K9/20 A61K38/10 A61K38/08 A61K47/04 A61K47/36 A61P15/04 

FIELD: medicine.

SUBSTANCE: group of inventions refers to postpartum haemorrhage treatment. Orally disintegrating solid pharmaceutical dosage unit for treating postpartum haemorrhage has weight ranging from 50 to 500 mg and consists of 1–100 wt. % particles, consisting of 0.01–10 wt. % of controlling the generic activity of oxytocin, 5–70 wt. % of buffer agent, 20–94 wt. % of branched glucan and 0–70 wt. % of other pharmaceutically acceptable ingredients; and 0–99 wt. % of one or more pharmaceutically acceptable excipients; wherein said solid dosing unit contains at least 5 mcg of the substance controlling the substance and has a buffer pH in range of 3.5–5.7. Also disclosed is the use of oxytocin for preparing a dosage unit for treating postpartum haemorrhage and a method for preparing a solid dosage unit.

EFFECT: group of inventions provides a stable dosing unit for treating postpartum haemorrhage.

10 cl, 8 tbl, 5 ex