LOCAL APPLICATION OF HSV ANTIBODY Russian patent published in 2019 - IPC C07K16/08 

Abstract RU 2703903 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to biotechnology, namely to use of HSV antibody and pharmaceutical composition for topical application in treating acute infection of mucous or epidermal tissue in individual. HSV antibody which recognizes HSV-1 and/or HSV-2 glycoprotein B (gB) and has the ability to inhibit the spread of HSV from the infected cell to a neighbouring second non-infected cell (cell-to-cell propagation), or its antigen-binding fragment for treating an acute mucosal or epidermal tissue infection in an individual caused by HSV-1 or HSV-2, which is selected from a group consisting of simple labial herpes, simple genital herpes, an infection which is a chronic or disseminated form of simple cutaneous herpes, herpes wrestlers-athletes and herpetiform eczema are used for topical application. Said antibody is contained in a pharmaceutical composition for topical application in treating an acute mucosal or epidermal tissue infection in an individual.

EFFECT: invention widens the range of equipment.

24 cl, 2 dwg, 1 tbl, 2 ex

Similar patents RU2703903C2

Title Year Author Number
NOVEL ANTI-PD-L1 ANTIBODIES 2016
  • Chzhen Yun
  • Li Tszin
  • Chen Chzhishen
RU2736151C2
MONOCLONAL ANTIBODY ABLE TO BIND TO SPECIFIC DISCONTINUOUS EPITOPE PLACED IN AD1 REGION OF HUMAN CYTOMEGALOVIRUS GB GLYCOPROTEIN, AND ITS ANTIGEN-BINDING FRAGMENT 2010
  • Takada, Kendzo
  • Kurino, Rika
  • Torasima, Takasi
RU2542472C2
gp41-NEUTRALIZING ANTIBODIES AND THEIR APPLICATION 2012
  • Konnors Mark
  • Khuan Tszinkhe
  • Laub Leo B.
  • Kvong Piter
  • Nejbel Gari
  • Maskola Dzhon R.
  • Chzhan Baoshan
  • Rudisell Rebekka S.
  • Dzhordzhiv Ivelin
  • Yang Jongping
  • Chzhu Tszyan
  • Ofek Dzhilad
RU2624046C2
NEUTRALISING ANTI-INFLUENZA A VIRUS ANTIBODIES AND USING THEM 2009
  • Lanzaveshija, Antonio
RU2553325C2
ANTIBODIES FOR TREATMENT OF HEPATITIS B INFECTION AND RELATED DISEASES 2018
  • Luo, Wenxin
  • Kang, Ciming
  • Wang, Yiwen
  • Yuan, Quan
  • Zhang, Tianying
  • Xia, Ningshao
RU2765878C2
HUMAN CYTOMEGALOVIRUS ANTIBODY AND USE THEREOF 2020
  • Lyao, Khuasin
  • Van, Yuemin
  • U, Chanven
  • Chzhen, Vejkhun
RU2817217C1
COMPOSITIONS AND METHODS OF TREATING INFECTIONS AND TUMOURS 2007
  • Akhmed Rafi
  • Amara Rama
  • Friman Gordon
  • Sharp Ehrlin
RU2540490C2
VACCINE AGAINST HERPES SIMPLEX VIRUS TYPE 2: COMPOSITIONS AND METHODS FOR TRIGGERING IMMUNE RESPONSE 2010
  • Long Debora
  • Flechtner Dzhessika
  • Skobern Mojka
  • Sajber Dzhorzh R.
RU2585961C9
PD-1 ANTIBODIES AND USE THEREOF 2016
  • Gu, Nana
  • Shao, Ke
RU2722451C1
SINGLE-DOMAIN ANTIBODIES DIRECTED AGAINST INTRACELLULAR ANTIGENS 2016
  • Singh, Sunanda
RU2741110C2

RU 2 703 903 C2

Authors

Arndt Mikhaela

Krauss Jyurgen

Eger Dirk

Dates

2019-10-22Published

2015-06-25Filed