NEUTRALISING ANTI-INFLUENZA A VIRUS ANTIBODIES AND USING THEM Russian patent published in 2015 - IPC C07K16/10 C12N15/13 C12N5/10 A61K39/395 A61P31/16 

Abstract RU 2553325 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: presented invention refers to immunology. There are presented versions of antibodies neutralising a subtype group 1 and subtype group 2 influenza A virus infection. The antibody is characterised by: either a set of 3 CDR of a light and 3 CDR of a heavy chain, or the presence of variable regions of the light and heavy chains. There are disclosed: a nucleic acid molecule coding the antibody; a cell expressing the antibody; as well as a method for the attenuation of the influenza A virus infection or reducing a risk thereof with the use of the antibody in a therapeutically or preventatively effective amount.

EFFECT: using the invention provides the antibodies neutralising the influenza A virus, which can find application in medicine in treating subtypes H1, H2, H3, H5, H7, H9 influenza.

18 cl, 6 tbl, 2 ex

Similar patents RU2553325C2

Title Year Author Number
IMMUNOGENIC EPITOPE OF INFLUENZA VIRUS 2009
  • Kutjur, Manon
  • Vezina, Lui-Filipp
  • Landri, Natali
RU2546872C2
ANTIBODIES SUITABLE FOR PASSIVE IMMUNIZATION AGAINST INFLUENZA, AND COMPOSITIONS THEREOF, COMBINATIONS AND METHODS OF USING 2015
  • Estelles Andzheles
  • Kauvar Lourens M.
  • Vigil Adam
  • Vittekind Majkl
RU2720282C1
STRAIN OF A RECOMBINANT PSEUDO ADENOVIRAL PARTICLE BASED ON HUMAN ADENOVIRUS GENOME OF SEROTYPE 5 Ad5-tetOFF-E3-HA125 SEROTYPE, CARRYING HAEMAGGLUTININ CONSENSUS GENE OF INFLUENZA VIRUS SUBTYPES H1, H2, H5 FOR PRODUCING INFLUENZA IMMUNOGENIC PREPARATIONS, METHOD FOR PRODUCING GENE 2018
  • Shmarov Maksim Mikhajlovich
  • Alekseeva Svetlana Viktorovna
  • Shcherbinin Dmitrij Nikolaevich
  • Lysenko Andrej Aleksandrovich
  • Sedova Elena Sergeevna
  • Artemova Elina Alekseevna
RU2713722C1
NEUTRALIZING ANTIBODIES TO INFLUENZA VIRUS B AND WAYS FOR APPLICATION THEREOF 2015
  • Korti Davide
  • Lantsavekkya Antonio
  • Kallevaard-Lelaj Nikol
  • Chzhu Tsin
  • Bendzhamin Eboni
  • Uochter Lesli
  • Yuan Endi
  • Makoliff Dzhozefin Meri
RU2711932C2
NEUTRALIZING BINDING MOLECULES DIRECTED AGAINST INFLUENZA VIRUS, AND METHODS OF THEIR APPLICATION 2016
  • Kallewaard-Lelay, Nicole
  • Zhu, Qing
  • Rainey, Godfrey, Jonah
  • Gao, Cuihua
  • Kasturirangan, Srinath
  • Gao, Changshou
RU2721706C2
OBTAINING VIRUS-LIKE PARTICLES OF INFLUENZA VIRUS IN PLANTS 2014
  • Couture, Manon
  • D Aoust, Marc-Andre
  • Vezina, Louis-Philippe
RU2742607C1
EXPRESSION VECTOR BASED ON HUMAN ADENOVIRUS 5 SEROTYPE, INDUCING CROSS-PROTECTIVE IMMUNITY TO INFLUENZA A VIRUSES OF SUBTYPE H1, AND A PHARMACEUTICAL COMPOSITION BASED ON IT 2023
  • Lysenko Andrei Aleksandrovich
  • Sedova Elena Sergeevna
  • Alekseeva Svetlana Viktorovna
  • Shcherbinin Dmitrii Nikolaevich
  • Tutykhina Irina Leonidovna
  • Verkhovskaia Liudmila Viktorovna
  • Avdonina Elena Dmitrievna
  • Bandeliuk Alina Sergeevna
  • Viskova Natalia Iurevna
  • Evgrafov Evgenii Valerevich
  • Dovzhenko Nina Aleksandrovna
  • Nikonova Alena Eduardovna
  • Kalugina Irina Alekseevna
  • Evgrafova Elina Alekseevna
  • Shmarov Maksim Mikhajlovich
  • Naroditskij Boris Savelevich
  • Logunov Denis Yurevich
  • Gintsburg Aleksandr Leonidovich
RU2802753C1
OBTAINING VIRUS-LIKE PARTICLES OF INFLUENZA VIRUS IN PLANTS 2014
  • Couture Manon
  • D'Aoust Marc-Andre
  • Vezina Louis-Philippe
RU2705555C2
H7N9 INFLUENZA A THERAPY 2015
  • Chai Ning
  • Mcbride Jacqueline
  • Swem Lee
RU2682049C2
NEUTRALIZING ANTIBODIES TO INFLUENZA VIRUS B AND WAYS OF THEIR APPLICATION 2015
  • Kallevaard-Lelaj, Nikol
  • Chzhu, Tsin
  • Bendzhamin, Eboni
  • Uochter, Lesli
  • Yuan, Endi
  • Makoliff, Dzhozefin, Meri
  • Korti, Davide
  • Lantsavekkya, Antonio
RU2739952C2

RU 2 553 325 C2

Authors

Lanzaveshija, Antonio

Dates

2015-06-10Published

2009-07-27Filed