FIELD: medicine.
SUBSTANCE: invention relates to medicine. Disclosed is a pharmaceutical composition exhibiting anti-tumor activity and containing as active compounds 2-amino-7-(diethylamino)-4-(4-methoxybenzo[d][1,3]dioxol-5-yl)-4H-chromene-3-carbonitrile (compound 1) or 2-aminium-7-(diethylamino)-4-(4-methoxybenzo[d][1,3]dioxol-5-yl)-4H-chromene-3-carbonitrile N-acetylaminoethanoate (compound 2) and pharmaceutically acceptable excipients in following ratio of components, wt %: active substance (compound 1 or 2) 5.0–30.0; pregelatinised corn starch 10.0–50.0; microcrystalline cellulose 5.0–60.0; colloidal silicon dioxide 1.0–5.0; stearic acid 0–1.0; sodium dodecyl sulphate 0–3.0; kollidone VA 64 0–3.0; Polysorbate 80 (Tween 80) 0–3.0.
EFFECT: technical result is obtaining low-toxic pharmaceutical compositions with anti-tumor activity based on compounds 1 or 2.
1 cl, 18 tbl, 12 ex
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