FIELD: chemistry.
SUBSTANCE: invention relates to hydrate of ciprofloxacin salt with 4-aminobenzoic acid, in which molar ratio of ciprofloxacin, 4-aminobenzoic acid and water is 1:1:1, having endothermic peaks from 70 to 80 °C and from 200 to 220 °C, according to measurement using differential scanning calorimetry (DSC analysis) having peaks at angle values 2θ(°) 7.3, 12.2, 12.8, 13.7, 14.7, 15.3, 16.8, 17.3, 18.0, 18.8, 20.5, 22.1, 23.5, 24.6, 24.4, 25.4, 25.9, 27.0, 27.5 by powder X-ray powder diffraction measurement data.
EFFECT: hydrate of ciprofloxacin salt with 4-aminobenzoic acid is obtained, having high solubility, suitable for use as a component of a pharmaceutical preparation for treating various bacterial infections.
1 cl, 7 dwg, 2 ex
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