FIELD: chemistry.
SUBSTANCE: present invention relates to a pharmaceutical salt of 8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-1-cyclopropyl-4-oxo-1,4-dihydro-3-quinoline carboxylic acid, characterised by that it is in form of a hydrochloride monohydrate and by solubility of at least 0.050 mg/ml water. The invention also relates to a pharmaceutical composition based on said pharmaceutical salt, use of said pharmaceutical salt and a method of treating or preventing bacterial infections based on use of said pharmaceutical salt.
EFFECT: obtaining a novel pharmaceutical salt of 8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-1-cyclopropyl-4-oxo-1,4-dihydro-3-quinoline carboxylic acid, characterised by good solubility in water, which influences bioavailability of the active ingredient.
7 cl, 16 dwg, 2 tbl, 9 ex
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Year |
Author |
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RU2077533C1 |
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SU1482531A3 |
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2020 |
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| DERIVATIVE OF 8-TRIFLUOROMETHYLQUINOLINE CARBOXYLIC ACID, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITION OF IMMUNODEFICIENCY VIRUS |
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1998 |
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2015 |
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RU2658821C1 |
