FIELD: chemistry.
SUBSTANCE: invention relates to new biologically active compounds – silver salts 3,4-diaryl-5-[4-(acetylaminosulfonyl)phenyl]-4,6-dihydropyrrolo[3,4-c]pyrazol-6-ones of formula (I, II, III), in which R1=4-CH3O, R2=4-Cl (I), R1=4-CH3O, R2=2-NO2 (II), R1=4-Br, R2=2-NO2 (III).
EFFECT: these compounds have antifungal activity and low toxicity.
1 cl, 1 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SILVER SALTS OF 5,6-DIARYL-4-[4-(ACETYLAMINOSULPHONYL)PHENYL]-3,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-ONES EXHIBITING ANTIMICROBIAL ACTIVITY | 2019 |
|
RU2698328C1 |
| APPLICATION OF THE SILVER SALT OF N-{4-[(1,3-THIAZOLE-2-YL)SULPHAMOYL]PHENYL}-1-PHENYL-5-(4-ETHOXYPHENYL)PYRAZOLE-3-CARBOXAMIDE AS AN ANTIFUNGAL AGENT AGAINST STRAINS OF C. TROPICALIS, C. KRUSEI, AND C. GLABRATA FUNGI | 2020 |
|
RU2763724C1 |
| USE OF SILVER SALTS OF METHYL (2Z)-4-ARYL-2-{4-[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFAMOYL]PHENYLAMINO}-4-OXOBUT-2-ENOATES AS ANTIBACTERIAL AGENTS | 2022 |
|
RU2793327C1 |
| DERIVATIVES OF PYRAZOLO(3,4-B)PYRIDINE | 1989 |
|
RU2022964C1 |
| ANALGESIC AGENT BASED ON 5-(2-AMINOPROPYL)-6-OXO-3,4-DIPHENYLPYRROLO[3,4-C]PYRAZOLE | 2020 |
|
RU2744162C1 |
| PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS TAM AND MET KINASE INHIBITORS | 2019 |
|
RU2773611C1 |
| ANALGESIC AGENTS BASED ON 5-ARYL-4-BENZOYL-3-HYDROXY-1-(4-GUANIDYLSULFONYLPHENYL)-3-PYRROLIN-2-ONES | 2016 |
|
RU2644161C2 |
| 3,4-DIMETHYL-6-(3-PYRIDYL)-N-PHENYL-2-OXO-1,2,3,6-TETRAHYDROPYRIMIDINE-5-CARBOXAMIDE WITH ANTIFUNGAL ACTIVITY AGAINST THE CANDIDA ALBICANS STRAIN | 2015 |
|
RU2649141C2 |
| USE OF 5-ARYL-4-AROYL-3-HYDROXY-1-CARBOXYMETHYL-3-PYRROLIN-2-ONES AS ANALGESICS | 2023 |
|
RU2816900C1 |
| DERIVATIVES OF 5H-PYRANO[2,3-D:6,5-D]DIPYRIMIDINE SHOWING ANTIBACTERIAL, ANTIVIRAL AND IMMUNOMODULATING EFFECT | 1997 |
|
RU2188201C2 |
