FIELD: pharmacopeia.
SUBSTANCE: present invention relates to the use of 5-(2-aminopropyl)-6-oxo-3,4-diphenylpyrrolo [3,4-c] pyrazole of formula (I) as an analgesic agent (I).
EFFECT: technical result of the present invention is the search in the series of pyrrolo [3,4-c] pyrazol-6-ones for a compound with a pronounced analgesic activity, increasing the reflex response time when irritating pain receptors and having low toxicity.
1 cl, 2 tbl
| Title |
Year |
Author |
Number |
| ANALGESIC AGENTS BASED ON 5-ARYL-4-BENZOYL-3-HYDROXY-1-(4-GUANIDYLSULFONYLPHENYL)-3-PYRROLIN-2-ONES |
2016 |
- Gejn Vladimir Leonidovich
- Bobrovskaya Olga Vasilevna
- Kovtonogova Irina Valerevna
- Chashchina Svetlana Viktorovna
- Yakovlev Igor Borisovich
|
RU2644161C2 |
| ETHYL 4-(5-BENZOYL-6-(4-(DIETHYLAMINO)PHENYL)-4-HYDROXY-2-THIOXOHEXAHYDROPYRIMIDIN-4-CARBOXAMINO)BENZOATE, EXHIBITING ANALGESIC AND ANTI-INFLAMMATORY ACTION |
2019 |
- Gejn Vladimir Leonidovich
- Gorgopina Ekaterina Vladimirovna
- Zamaraeva Tatyana Mikhajlovna
- Rudakova Irina Pavlovna
- Dozmorova Natalya Viktorovna
|
RU2717246C1 |
| 5-(4-HYDROXYPHENYL)-4-(4-METHOXYBENZOYL)-3-HYDROXY-1-(2,2-DIMETHOXYETHYL)-3-PYRROLIN-2-ONE, EXHIBITING ANALGESIC AND ANTIPYRETIC PROPERTIES |
2009 |
- Levandovskaja Elena Boleslavovna
- Gejn Vladimir Leonidovich
- Syropjatov Boris Jakovlevich
- Vychegzhanina Viktorija Nikolaevna
- Kovaleva Marina Jur'Evna
- Danilova Natalija Vladimirovna
|
RU2429229C1 |
| USE OF METHYL 5-BENZOYL-4-HYDROXY-6-(4-CHLOROPHENYL)-2-THIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLATE AS AN AGENT HAVING ANALGESIC AND ANTI-INFLAMMATORY ACTION |
2024 |
- Zamaraeva Tatiana Mikhailovna
- Rudakova Irina Pavlovna
- Gorgopina Ekaterina Vladimirovna
|
RU2835600C1 |
| USE OF 3,4-DIMETHYL-6-(3-NITROPHENYL)-2-OXO-N-PHENYL-1,2,3,6-TETRAHYDROPYRIMIDINE-5-CARBOXAMIDE AS AGENT WITH ANALGESIC ACTIVITY |
2022 |
- Gein Vladimir Leonidovich
- Zamaraeva Tatiana Mikhailovna
- Rudakova Irina Pavlovna
|
RU2785688C1 |
| USE OF 4-[1-(4-METHYLPHENYL)AMINOETHYLIDENE]-5-PHENYL-1-CYANOMETHYLTETRAHYDROPYRROLE-2,3-DIONE AS AN ANALGESIC |
2023 |
- Gein Vladimir Leonidovich
- Buldakova Evgeniia Anatolevna
- Gein Oksana Nikolaevna
|
RU2806330C1 |
| USE OF 4-(4-BROMOPHENYL)-6-METHYL-2-THIOXO-N-(O-TOLYL)-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXAMIDE AS AGENT HAVING ANALGESIC ACTIVITY |
2024 |
- Zamaraeva Tatiana Mikhailovna
- Buzmakova Nadezhda Albertovna
- Podchezertseva Karina Vladimirovna
|
RU2835601C1 |
| 4-METHYL-N-2,4-DIMETHYLPHENYL-6-(3-FLUOROPHENYL)-2-THYOXO-1,2,3,6-TETRAGYDROPYRIMIDINE-5-CARBOXAMIDE THAT HAS ANALGETIC ACTION |
2015 |
- Gejn Vladimir Leonidovich
- Zamaraeva Tatyana Mikhajlovna
- Buzmakova Nadezhda Albertovna
- Syropyatov Boris Yakovlevich
- Alikina Nataliya Viktorovna
|
RU2653511C2 |
| USE OF 4-(4-BROMOPHENYL)-6-METHYL-N-(2-CHLOROPHENYL)-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXAMIDE AS AN AGENT WITH ANALGESIC ACTIVITY |
2022 |
- Gein Vladimir Leonidovich
- Zamaraeva Tatiana Mikhailovna
- Rudakova Irina Pavlovna
|
RU2793550C1 |
| USE OF 5-BENZOYL-4-HYDROXY-N-(4-IODOPHENYL)-6-(4-CHLOROPHENYL)-2-OXOHEXAHYDROPYRIMIDINE-4-CARBOXAMIDE AS AGENT WITH ANALGESIC ACTIVITY |
2023 |
- Gorgopina Ekaterina Vladimirovna
- Zamaraeva Tatiana Mikhailovna
- Rudakova Irina Pavlovna
- Gein Vladimir Leonidovich
|
RU2811249C1 |
