FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to pharmaceutics, and can be used for selection of anthranilic acid derivatives possessing anti-inflammatory action. For this purpose, binding energy of anthranilic acid derivatives with cyclooxygenases (COX) 1 and 2 (BeCOX1 and BeCOX2). Provided that BeCOX1 is in intervals ((-1.31)–(-1.67); (-3.87)–(-5.34); (-6.12)–(-9.12)) and BeCOX2 is in the ranges (-5.78)–(-6.11); (-6.19)–(-9.45)), an anthranilic acid derivative is considered having anti-inflammatory action.
EFFECT: invention enables to search for substances with anti-inflammatory activity.
1 cl, 5 tbl, 23 ex
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