NONSTEROID ANTI-INFLAMMATORY AGENT ON BASIS OF NAPROXEN WITH LOW GASTROTOXICITY Russian patent published in 2017 - IPC C07D213/67 A61K31/4415 A61P29/00 

Abstract RU 2629367 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to a new naproxen derivative of the formula (I)

,

3-((S)-2-(6-methoxynaphth-2-yl)propanoyloxy)-4.5-bis(((S)-2-(6-methoxynaphth-2-yl)propanoyloxy)methyl)-2-methylpyridinium(S)-2-(6-methoxynaphth-2-yl)propanoate.

EFFECT: high anti-inflammatory, analgesic and antipyretic activity, low acute toxicity and gastrotoxicity.

7 tbl, 2 ex

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RU 2 629 367 C1

Authors

Shtyrlin Yurij Grigorevich

Pavelev Roman Sergeevich

Iksanova Alfiya Gabdulakhatovna

Shtyrlin Nikita Valerevich

Pugachev Mikhail Vladimirovich

Balakin Konstantin Valerevich

Ajmaletdinov Aleksandr Maazovich

Ganiev Ilnur Makhmutovich

Malaneva Albina Gennadevna

Dates

2017-08-29Published

2016-11-02Filed