IGF-1R ANTIBODY AND USE THEREOF FOR DIAGNOSING CANCER Russian patent published in 2019 - IPC C07K16/28 G01N33/574 G01N33/68 A61K39/395 A61P35/00 

Abstract RU 2706967 C2

FIELD: medicine.

SUBSTANCE: present invention relates to immunology. Antibodies to an insulin-like growth factor receptor 1 (IGF-1R) and their antigen-binding fragments are offered. Also disclosed is a method of detecting the presence and/or localization of tumour cells, a method of determining the percentage of tumour cells, a method for determining the level of expression of IGF-1R in tumour cells, a method for determining quantitative evaluation of IGF-1R tumour cells or tumour. Also described is a method for determining whether an oncogenic disease is susceptible to treatment, method for determining the effectiveness of a therapeutic regimen, a method for selecting a patient, as well as a kit for detecting tumour cells and a kit for determining whether the drug treatment is beneficial for a patient suffering oncogenic disorder.

EFFECT: present invention can find further application in therapy of oncogenic diseases, particularly cancer.

15 cl, 9 dwg, 6 tbl, 3 ex

Similar patents RU2706967C2

Title Year Author Number
IGF-1R ANTIBODY AND USE THEREOF FOR DIAGNOSING CANCER 2016
  • Zhuanno, Aleksandra
RU2706959C2
I-3859 ANTIBODY APPLICATION FOR CANCER DETECTION AND DIAGNOSTICS 2012
  • Klinger-Amur Kristin
  • Zhuanno Aleksandra
RU2636032C2
NEW ANTIBODY TO CXCR4 AND ITS APPLICATION FOR CANCER DETECTION AND DIAGNOSTICS 2012
  • Klinger-Amur Kristin
  • Zhuanno Aleksandra
  • Zhanen-Bussa Mari-Kler
RU2636345C2
ANTI-cMet ANTIBODY AND USE THEREOF FOR DETECTION AND DIAGNOSIS OF CANCER 2010
  • Getsh Lilian
  • Zhuanno Aleksandra
RU2582265C2
NEW MODULATORS AND METHODS OF THEIR APPLICATION 2012
  • Foord Orit
  • Dylla Scott J.
  • Stull Robert A.
  • Bankovich Alex
  • Lazetic Alexandra Leida Liana
  • Bernstein Jeffrey
RU2627176C2
NOVEL ANTIBODY FOR DIAGNOSIS AND/OR PROGNOSIS OF CANCER 2011
  • Zhuanno Aleksandra
RU2651513C2
HUMANISED ANTI-CXCR4 ANTIBODIES FOR TREATING CANCER 2011
  • Klinger-Amur Kristin
  • Zhuanno Aleksandra
  • Grene-Kossanel Veronik
  • Berger Sven
RU2595394C2
COMPOSITION FOR TREATING IGF-1R EXPRESSING CANCER 2016
  • Zhuanno Aleksandra
  • Getsh Lilian
  • Brussa Matte
  • Bo-Larvor Sharlott
  • Shampen Terri
  • Rober Alen
  • Ev Zhan-Fransua
  • Rilatt Ian
  • Peres Mishel
RU2728568C2
NOVEL MODULATORS AND METHODS FOR USE THEREOF 2011
  • Hampl Johannes
  • Dylla Scott J.
  • Foord Orit
  • Stull Robert A.
RU2592672C9
ANTI-IGF-1R ANTIBODY AND USE THEREOF AS AN ADDRESS VECTOR FOR CANCER TREATMENT 2015
  • Getsh Lilian
  • Brussa Matte
  • Bo-Larvor Sharlott
  • Shampen Terri
  • Rober Alen
RU2698977C2

RU 2 706 967 C2

Authors

Zhuanno, Aleksandra

Dates

2019-11-21Published

2016-04-27Filed