COMPOSITION FOR TREATING IGF-1R EXPRESSING CANCER Russian patent published in 2020 - IPC A61K47/68 A61K39/395 A61P35/00 

Abstract RU 2728568 C2

FIELD: medicine.

SUBSTANCE: method and a kit for treating cancer expressing IGF-1R are disclosed. An anti-IGF-1R antibody and an antibody-drug conjugate of formula Ab-(L-D)n or a pharmaceutically acceptable salt thereof are used.

EFFECT: proposed group of inventions enables to determine the status of IGF-1R cancer by using a first antibody and use a second antibody as ADC (antibody-drug conjugate) for treating cancer.

11 cl, 39 dwg, 18 tbl, 27 ex

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RU 2 728 568 C2

Authors

Zhuanno Aleksandra

Getsh Lilian

Brussa Matte

Bo-Larvor Sharlott

Shampen Terri

Rober Alen

Ev Zhan-Fransua

Rilatt Ian

Peres Mishel

Dates

2020-07-30Published

2016-10-26Filed