FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to application of an isolated antibody to CXCR4 in the diagnosis of cancer, which can be used in medicine. In particular, methods for diagnosis and/or prediction of an oncogenic disorder associated with CXCR4 expression, determination whether the disorder or treated patient are susceptible to treatment with an anti-CXCR4 antibody, methods for determination of an effective treatment regimen, and kits for treatment of the said diseases are disclosed.
EFFECT: invention allows effective diagnosis and therapy of oncogenic disorders characterized by CXCR4 expression.
18 cl, 7 dwg, 3 tbl, 7 ex
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Authors
Dates
2017-11-17—Published
2012-07-30—Filed