METHOD OF PRODUCING N-CYANOMETHYLIMIDAZO[4,5-E]BENZO[1,2-C;3,4-C']DIFUROXANE Russian patent published in 2019 - IPC C07D498/14 

Abstract RU 2707296 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, specifically to a method of producing N-cyanomethylimidazo[4,5-e]benzo[1,2-c; 3,4-c']difuroxane. Method is characterized by that alkylation of imidazo[4,5-e]benzo[1,2-c; 3,4-c']difuroxane is carried out with bromoacetonitrile in dimethylformamide medium.

EFFECT: disclosed method reduces reaction time and increases output of the product.

1 cl, 1 dwg, 1 ex

Similar patents RU2707296C1

Title Year Author Number
METHOD OF PRODUCING N-ALLYLIMIDAZO[4,5-E]BENZO[1,2-C;3,4-C']DIFUROXANE 2019
  • Korolev Vyacheslav Leonidovich
  • Merkulova Natalya Leonidovna
  • Lotorev Dmitrij Sergeevich
  • Kuznetsov Pavel Evgenevich
  • Maksimov Vladimir Alekseevich
  • Kudryavtseva Tatyana Nikolaevna
RU2718905C1
METHOD OF PRODUCING N-CARBETHOXYMETHYL-C-METHYLIMIDAZO[4,5-E]BENZO[1,2-C;3,4-C']DIFUROXANE 2020
  • Korolev Vyacheslav Leonidovich
  • Merkulova Natalya Leonidovna
  • Lotorev Dmitrij Sergeevich
  • Kuznetsov Pavel Evgenevich
  • Maksimov Vladimir Alekseevich
  • Kudryavtseva Tatyana Nikolaevna
RU2725631C1
METHOD OF OBTAINING C-NITROIMIDAZO[4,5-E]BENZO[1,2-C;3,4-C']DIFUROXANE 2018
  • Korolev Vyacheslav Leonidovich
  • Merkulova Natalya Leonidovna
  • Danilenko Vitalij Mikhajlovich
  • Pivina Tatyana Stepanovna
  • Lotorev Dmitrij Sergeevich
  • Kudryavtseva Tatyana Nikolaevna
RU2675159C1
METHOD OF PRODUCING C-NITROIMIDAZO[4,5-E]BENZO[1,2-C;3,4-C']DIFUROXANE 2019
  • Korolev Vyacheslav Leonidovich
  • Merkulova Natalya Leonidovna
  • Danilenko Vitalij Mikhajlovich
  • Pivina Tatyana Stepanovna
  • Lotorev Dmitrij Sergeevich
  • Kudryavtseva Tatyana Nikolaevna
RU2700931C1
METHOD OF PRODUCING C-HYDROXYMETHYLIMIDAZO[4,5-E]BENZO[1,2-C; 3,4-C']DIFUROXANE 2019
  • Korolev Vyacheslav Leonidovich
  • Merkulova Natalya Leonidovna
  • Danilenko Vitalij Mikhajlovich
  • Pivina Tatyana Stepanovna
  • Lotorev Dmitrij Sergeevich
  • Kudryavtseva Tatyana Nikolaevna
RU2692680C1
METHOD FOR PRODUCTION OF N-CARBETHOXYMETHYLIMIDAZO[4,5-E]BENZO[1,2-C;3,4-C']DIFUROXANE 2017
  • Lotorev Dmitrij Sergeevich
  • Brylev Maksim Igorevich
  • Alekseev Aleksej Anatolevich
  • Korolev Vyacheslav Leonidovich
  • Merkulova Natalya Leonidovna
  • Kudryavtseva Tatyana Nikolaevna
RU2663846C1
METHOD FOR PRODUCING N-CARBETOXIMETHYLIMIDEAZO[4,5-e]BENZO[1,2-c;3,4-c']DYFUROXANE 2016
  • Korolev Vyacheslav Leonidovich
  • Toporov Vladislav Vladimirovich
  • Danilenko Vitalij Mikhajlovich
  • Ivshin Viktor Pavlovich
  • Lotorev Dmitrij Sergeevich
  • Pavlova Lyudmila Anatolevna
RU2618230C1
N-CARBOXYMETHYLIMIDAZO[4,5-e]BENZO[1,2-c;3,4-c']DIFUROXANE 2014
  • Korolev Vjacheslav Leonidovich
  • Toporov Vladislav Vladimirovich
  • Danilenko Vitalij Mikhajlovich
  • Ivshin Viktor Pavlovich
  • Alekseev Aleksej Anatol'Evich
  • Pavlova Ljudmila Anatol'Evna
RU2544547C1
THROMBOCYTE AGGREGATION-INHIBITING HETEROMERIC PEPTIDES BASED ON IMIDAZO[4,5-e]BENZO[1,2-c;3,4-c']DIFUROXANE 2014
  • Alekseev Aleksej Anatol'Evich
  • Brylev Maksim Igorevich
  • Korolev Vjacheslav Leonidovich
  • Lotorev Dmitrij Sergeevich
  • Lizunov Anton Jur'Evich
  • Pavlova Ljudmila Anatol'Evna
  • Belushkina Natal'Ja Nikolaevna
RU2550223C1
THROMBOCYTE AGGREGATION-INHIBITING N-CARB(ARGINYL)OXYMETHYLIMIDAZO[4,5-e]BENZO[1,2-c;3,4-c']DIFUROXANE 2014
  • Alekseev Aleksej Anatol'Evich
  • Brylev Maksim Igorevich
  • Korolev Vjacheslav Leonidovich
  • Lotorev Dmitrij Sergeevich
  • Batuev Evgenij Andreevich
  • Pavlova Ljudmila Anatol'Evna
  • Belushkina Natal'Ja Nikolaevna
RU2549355C1

RU 2 707 296 C1

Authors

Korolev Vyacheslav Leonidovich

Merkulova Natalya Leonidovna

Lotorev Dmitrij Sergeevich

Pivina Tatyana Stepanovna

Kuznetsov Pavel Evgenevich

Maksimov Vladimir Alekseevich

Kudryavtseva Tatyana Nikolaevna

Dates

2019-11-26Published

2019-07-31Filed