LIGAND CONJUGATE WITH CYTOTOXIC DRUG PREPARATION, METHOD AND APPLICATION THEREOF Russian patent published in 2019 - IPC A61K47/68 C07K7/06 C07K16/30 C07D207/08 C07D207/20 A61P35/00 

Abstract RU 2708461 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to a conjugate of a ligand with a cytotoxic drug of general formula PC-LD, a method for its preparation and pharmaceutical compositions containing it for preparing medicinal agents for treating cancer.

EFFECT: disclosed is a conjugate of a ligand with a cytotoxic drug, a method for production thereof and use.

18 cl, 5 tbl, 53 ex

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RU 2 708 461 C2

Authors

Syuj Tszyanyan

Chzhan In

Tsyuj Bolej

Chzhan Fuyao

Yuj Syuchzhao

Lian Tszindun

Tszyan Gujyan

Chzhan Lyanshan

Li An

Van Yali

Dates

2019-12-09Published

2016-01-26Filed