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2 709 527

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(51)

IPC

A61K38/08(2006-01-01)

A61P1/14(2006-01-01)

A61P39/00(2006-01-01)

(21) (22)

Application

2019124360, 2019-07-29

(24)

Start date

2019-07-29

(22)

Actual filing date

2019-07-29

(45)

Published

2019-12-18

(72)

Inventor

Svishcheva Mariya VladimirovnaMukhina Aleksandra YurevnaMedvedeva Olga AnatolevnaKalutskij Pavel VyacheslavovichShevchenko Alina VladimirovnaBobyntsev Igor IvanovichAndreeva Lyudmila AleksandrovnaMyasoedov Nikolaj Fedorovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

USE OF PEPTIDE Met-Glu-His-Phe-Pro-Gly-Pro (Semax) FOR DYSBIOSIS CORRECTION IN CHRONIC IMMOBILIZATION STRESS Russian patent published in 2019 - IPC A61K38/08 A61P1/14 A61P39/00

Abstract RU 2709527 C1

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention refers to medicine and pharmacy. Disclosed is the use of the Met-Glu-His-Phe-Pro-Gly-Pro (Semax) heptapeptide for the dysbiosis correction in chronic immobilization stress. Technical result of invention is implementation of assignment, wherein in intestinal biopsy material content of lactobacilli, bifidobacteria, Escherichia coli with normal fermentative activity, enterococci was significantly higher than in absence of treatment in chronic immobilizing stress; content of fungus Candida, Proteus spp., Klebsiella spp., Morganella spp., conversely, significantly reduced.

EFFECT: invention provides an increase in the efficiency of dysbiosis correction under chronic immobilization stress.

1 cl, 1 tbl

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RU 2 709 527 C1

Authors

Svishcheva Mariya Vladimirovna

Mukhina Aleksandra Yurevna

Medvedeva Olga Anatolevna

Kalutskij Pavel Vyacheslavovich

Shevchenko Alina Vladimirovna

Bobyntsev Igor Ivanovich

Andreeva Lyudmila Aleksandrovna

Myasoedov Nikolaj Fedorovich

Dates

2019-12-18—Published

2019-07-29—Filed