FIELD: pharmaceuticals.
SUBSTANCE: invention relates to the use of the Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selang) peptide for the correction of dysbiosis under chronic immobilization stress. Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selang) peptide was dissolved in physiological saline and administered to experimental animals (rats) parenterally (intraperitoneally) at a dose of 250 mcg/kg body weight 15 minutes before the onset of stress in the volume of calculating 1 ml per 1 kg of body weight.
EFFECT: invention provides an increase in the efficiency of dysbiosis correction under chronic immobilization stress.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| APPLICATION OF THE HIS-PHE-ARG-TRP-PRO-GLY-PRO PEPTIDE FOR THE PREVENTION OF DYSBIOSIS IN CHRONIC IMMOBILIZATION STRESS | 2021 |
|
RU2770583C1 |
| USE OF PEPTIDE Met-Glu-His-Phe-Pro-Gly-Pro (Semax) FOR DYSBIOSIS CORRECTION IN CHRONIC IMMOBILIZATION STRESS | 2019 |
|
RU2709527C1 |
| USE OF PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANC) HEPATOPROTECTIVE FOR EXPOSURE IN ACUTE IMMOBILISATION STRESS | 2015 |
|
RU2582963C1 |
| APPLICATION OF THR-LYS-PRO-ARG-PRO-GLY-PRO PEPTIDE (SELANK) FOR HEPATOPROTECTIVE IMPACT IN CHRONIC EMOTIONAL-PAIN STRESS | 2016 |
|
RU2629832C1 |
| APPLICATION OF Thr-Lys-Pro-Arg-Pro-Gly-Pro PEPTIDE (SELANK) FOR TOXIC HEPATITIS PREVENTION AND TREATMENT | 2017 |
|
RU2640133C1 |
| USE OF THE PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANK) TO INCREASE BODY RESISTANCE TO ACUTE HYPOTHERMIA | 2019 |
|
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| METHOD FOR PREVENTING AND TREATING ULCERS OF GASTRO-INTESTINAL TRACT | 2003 |
|
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| ANXIOLYTIC AGENT AND PHARMACEUTICAL COMPOSITION WITH ANXIOLYTIC EFFECT | 1999 |
|
RU2155065C1 |
| AGENT POSSESSING ANTI-COAGULATING, ANTI-THROMBOCYTIC, ANTI-THROMBOSIS, FIBRIN-DEPOLYMERIZING AND FIBRINOLYTIC ACTIVITY | 2005 |
|
RU2290195C1 |
| AGENT FOR REDUCTION OF INTESTINAL MICROBIOCENOSIS IN CASE OF DYSBIOSIS | 2015 |
|
RU2593584C1 |
