FIELD: medicine.
SUBSTANCE: invention relates to the use of the His-Phe-Arg-Trp-Pro-Gly-Pro peptide for the prevention of dysbiosis in chronic immobilization stress. His-Phe-Arg-Trp-Pro-Gly-Pro peptide was dissolved in physiological saline and administered to experimental animals (rats) parenterally (intraperitoneally) at a dose of 500 μg/kg of body weight 15 minutes before the onset of stress exposure in a volume of 1 ml per 1 kg of body weight.
EFFECT: invention provides an increase in the efficiency of preventing dysbiosis in chronic immobilization stress.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| USE OF PEPTIDE Met-Glu-His-Phe-Pro-Gly-Pro (Semax) FOR DYSBIOSIS CORRECTION IN CHRONIC IMMOBILIZATION STRESS | 2019 |
|
RU2709527C1 |
| APPLICATION OF PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANG) FOR DYSBIOSIS CORRECTION UNDER CHRONIC IMMOBILIZATION STRESS | 2018 |
|
RU2681217C1 |
| USE OF PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANC) HEPATOPROTECTIVE FOR EXPOSURE IN ACUTE IMMOBILISATION STRESS | 2015 |
|
RU2582963C1 |
| APPLICATION OF THR-LYS-PRO-ARG-PRO-GLY-PRO PEPTIDE (SELANK) FOR HEPATOPROTECTIVE IMPACT IN CHRONIC EMOTIONAL-PAIN STRESS | 2016 |
|
RU2629832C1 |
| USE OF PEPTIDE MET-GLU-HIS-PHE-PRO-GLY-PRO (SEMAX) FOR MAINTAINING VEGETATIVE BALANCE DURING PHYSICAL ACTIVITY | 2023 |
|
RU2813468C1 |
| UNIFORM DEUTERIUM- OR YTTRIUM-LABELLED His-Phe-Arg-Trp-Pro-Gly-Pro | 2014 |
|
RU2544016C1 |
| USE OF MET-GLU-HIS-PHE-PRO-GLY-PRO (SEMAX) PEPTIDE TO ACHIEVE ADAPTOGENIC EFFECT DURING SHORT-TERM PHYSICAL ACTIVITY | 2023 |
|
RU2813470C1 |
| APPLICATION OF Thr-Lys-Pro-Arg-Pro-Gly-Pro PEPTIDE (SELANK) FOR TOXIC HEPATITIS PREVENTION AND TREATMENT | 2017 |
|
RU2640133C1 |
| USE OF PEPTIDE ACTH (4-7) -PGP OF HEPATOPROTECTIVE ACTION | 2013 |
|
RU2528741C1 |
| USE OF THE PEPTIDE GLY-HIS-LYS-PRO-GLY-PRO TO ACHIEVE AN ANTIDEPRESSANT EFFECT | 2020 |
|
RU2747224C1 |
