DERIVATIVES OF BISAMIDES OF DICARBOXYLIC ACIDS, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON, METHODS FOR PRODUCTION THEREOF Russian patent published in 2019 - IPC C07D403/12 A61K31/4178 A61P31/12 A61P9/00 A61P3/10 A61P25/28 A61P25/32 A61P39/02 

Abstract RU 2709529 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a bisamide derivative of dicarboxylic acid of formula 10, which is capable of complexing or chelating metal ions. Invention also relates to use of a derivative of formula 10 and a medicinal agent based thereon for preventing and/or treating cardiovascular, viral, oncological, neurodegenerative, inflammatory diseases, diabetes, gerontological diseases, diseases caused by toxins of microorganisms, as well as alcoholism, alcoholic hepatic cirrhosis, anaemia, late porphyria, poisonings with salts of transition metals in humans and animals. Invention also relates to pharmaceutical compositions based on a dicarboxylic acid derivative of formula 10, methods for preventing and/or treating said diseases in humans and animals and to methods of producing a dicarboxylic acid derivative of formula 10.

formula 10.

EFFECT: technical result is obtaining a biocompatible heterocyclic chelator of metal ions and use thereof for treating and/or preventing said diseases.

68 cl, 5 tbl, 9 ex

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RU 2 709 529 C1

Authors

Nebolsin Vladimir Evgenevich

Kromova Tatyana Aleksandrovna

Zheltukhina Galina Aleksandrovna

Dates

2019-12-18Published

2018-08-06Filed