COMPOSITIONS AND METHODS OF PREVENTING INFECTIONS Russian patent published in 2020 - IPC A61K35/741 A61P1/00 A61J3/07 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: present group of inventions refers to pharmaceutical industry, namely to a method for maintaining a healthy intestine. Method for maintaining a healthy bowel condition selected from maintaining the balance of intestinal flora, maintaining a good functional state of the intestine, providing normal operation of the intestine in the subject, comprising administering an effective amount of a composition containing lyophilised Saccharomyces boulardii as an active substance, wherein the composition is in a closed flask having a first sealed compartment containing a powder of lyophilised S. boulardii, and a second compartment containing a solution containing water, wherein the first and second compartments can be brought into a sealed connection with each other to obtain a suspension S. boulardii for administration to a subject after opening the flask, and wherein the suspension is administered orally. Method for maintaining balance of intestinal flora, maintaining good functional state of intestine, providing normal operation of intestine and/or maintaining a healthy intestine, for preventing or treating disturbed balance of microflora in the gastrointestinal tract, selected from diarrhoea and/or bacterial, fungal or protozoal infections, antibiotic-associated diarrhoea, travelers' diarrhoea, diarrhoea related to enteral nutrition, acute gastroenteritis in adults or children, HIV-associated diarrhoea or lambliasis, or for use as an additional symptomatic treatment of diarrhoea in addition to rehydration, for preventing or treating an infection caused by Clostridium difficile, infection caused by Helicobacter pylori, infection caused by Salmonella, infection caused by Shigella, infection caused by Cryptosporidium, or oral cavity candidiasis, for preventing or treating an inflammatory bowel disease or irritable bowel syndrome in a subject. Method for reducing the risk of fungemia caused by Saccharomyces boulardii in a subject.

EFFECT: above described methods are effective for reducing risk of fungemia in treating intestinal disorders.

11 cl, 1 dwg, 1 ex