COMPOUNDS FOR TREATING CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASES Russian patent published in 2016 - IPC C07D401/14 C07D403/14 C07D405/14 C07D407/14 C07D409/14 C07D417/14 A61K31/4439 A61P31/04 

Abstract RU 2575477 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to organic chemistry, namely to a bibenzoimidazol derivative of general formula wherein R1 is pyridyl; R2 represents an aromatic 9-merous bicyclic ring system, wherein one or two carbon atoms can be substituted by N, O, or S; or to its pharmaceutically acceptable salt, hydrate or solvate. The invention also refers to a combination based on the compound of formula (I) and an additional specified agent, a pharmaceutical composition based on the compound of formula (I), a method of treating Clostridium difficile infection and a method of eliminating Clostridium difficile bacterium.

EFFECT: produced are new bibenzoimidazol derivatives possessing effective biological properties.

14 cl, 2 tbl, 2 ex

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RU 2 575 477 C2

Authors

Dzhonson Piter Dejvid

Vikers Richard

Uilson Frehnsis Ksav'E

Dorgen Kolin Richard

Sadlou Loren Dzhejn

Ren Stiven Pol

Van Vell Renate

Dates

2016-02-20Published

2011-06-01Filed