INTRANASAL ADMINISTRATION Russian patent published in 2020 - IPC A61M15/08 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medical equipment. Nasal tip for delivering a substance into a nasal cavity of a subject comprises a first, an internal, a body portion and a second, outer, body portion which is located at least around the distal region of the inner body portion and forms an end member. Inner body part comprises a base, which comprises a flow channel, and a blade-shaped projection in the distal end, which supports the end element and stiffness in the sagittal direction, which enables the end element to open the fleshy tissue in the upper region of the nasal valve and thereby increase the cross-sectional area of the open nose valve, as well as lateral flexibility perpendicular to the sagittal plane, which facilitates insertion of the end element into the nasal valve. An alternative embodiment of making a nose tip and an intranasal delivery device comprising a nose tip are disclosed.

EFFECT: inventions provide effective delivery of peptides for treating narcolepsy and diabetes.

38 cl, 14 dwg, 10 tbl