FIELD: chemistry.
SUBSTANCE: invention relates to polymer conjugates of a hexahedral platinum complex. Disclosed is a polymer conjugate of hexa-coordinated platinum complex, in which hexa-coordinated platinum complex containing halogens and hydroxyl groups in axial positions, directly or through spacers are bonded with side chain carboxyl groups of block copolymer containing polyethylene glycol structural fragment and fragment of polyaspartic acid or fragment of polyglutamic acid.
EFFECT: technical result is that the disclosed conjugate effectively releases a highly active complex of platinum under reducing conditions, including in cells.
16 cl, 2 dwg, 7 tbl, 21 ex
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