FIELD: biomedical research.
SUBSTANCE: group of inventions relates to compounds which can be used for diagnosing tumors. Disclosed is a fluorescent conjugate containing a fluorochrome F fragment connected to a targeting moiety T, where fragment F has formula (I):
.
Targeting fragment T has an affinity for the tumor marker. Also disclosed are use of a conjugate for diagnosing tumors in vitro or in vivo, including photodetection of tumor nodes during resection surgical treatment.
EFFECT: disclosed are fluorescent conjugates and use thereof for diagnosing tumors.
24 cl, 4 dwg, 1 tbl, 7 ex
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Authors
Dates
2020-05-15—Published
2016-06-02—Filed