FLUORESCENT CONJUGATES AND USE THEREOF FOR TUMOR DIAGNOSTICS Russian patent published in 2020 - IPC A61K31/473 A61K39/395 A61K49/00 G01N33/574 G01N33/533 C07K16/30 A61B10/00 A61P35/00 

Abstract RU 2720976 C2

FIELD: biomedical research.

SUBSTANCE: group of inventions relates to compounds which can be used for diagnosing tumors. Disclosed is a fluorescent conjugate containing a fluorochrome F fragment connected to a targeting moiety T, where fragment F has formula (I):

.

Targeting fragment T has an affinity for the tumor marker. Also disclosed are use of a conjugate for diagnosing tumors in vitro or in vivo, including photodetection of tumor nodes during resection surgical treatment.

EFFECT: disclosed are fluorescent conjugates and use thereof for diagnosing tumors.

24 cl, 4 dwg, 1 tbl, 7 ex

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RU 2 720 976 C2

Authors

Kaje, Fransuaza

Frameri, Berenike

Dates

2020-05-15Published

2016-06-02Filed