FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and immunology. Separated antibodies and fragments thereof are described, which bind to tumour antigens. Also are described compositions and vehicle agents, which include expandable antibodies; cells which produce these antibodies; methods for producing antibodies; methods for using these antibodies targeted on tumour and/or metastatic cells formed by tumours, and/or tumour stem cells, and treatment of tumours and/or metastatic cells formed by them, and/or tumour stem cells; and methods for prediction of recurrent cancer in subjects.
EFFECT: presented group of inventions can be applied in medicine.
22 cl, 22 dwg, 4 tbl, 8 ex
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