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(19)

(11)

2 722 363

(13)

(51)

IPC

A61K31/437(2006-01-01)

A61K31/4985(2006-01-01)

A61K31/506(2006-01-01)

A61K31/5383(2006-01-01)

A61P35/00(2006-01-01)

A61P43/00(2006-01-01)

C07D401/14(2006-01-01)

C07D403/14(2006-01-01)

C07D471/04(2006-01-01)

C07D487/08(2006-01-01)

C07D487/10(2006-01-01)

C07D498/04(2006-01-01)

(21) (22)

Application

2017131559, 2016-03-10

(24)

Start date

2016-03-10

(22)

Actual filing date

2016-03-10

(45)

Published

2020-05-29

(72)

Inventor

Din, Charlz Z.Chen, ShukhuejChzhao, BaopinSyu, ChzhaobinLyu, InchunLin, RujbinVan, FejLi, Tszyan

(73)

Holder

Chia Taj Tyantsin Farmasyutikal Grup Ko., Ltd.

SUBSTITUTED 2H-PYRAZOLE DERIVATIVE Russian patent published in 2020 - IPC A61K31/437 A61K31/4985 A61K31/506 A61K31/5383 A61P35/00 A61P43/00 C07D401/14 C07D403/14 C07D471/04 C07D487/08 C07D487/10 C07D498/04

Abstract RU 2722363 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to novel substituted 2H-pyrazole derivative acting as a selective inhibitor of CDK4/6. In particular, the disclosed invention is a substance of formula (I) or a pharmaceutically acceptable salt thereof, which acts as a selective inhibitor of CDK4/6.

EFFECT: disclosed is substituted 2H-pyrazole derivative.

18 cl, 4 tbl, 35 ex

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RU 2 722 363 C2

Authors

Din, Charlz Z.

Chen, Shukhuej

Chzhao, Baopin

Syu, Chzhaobin

Lyu, Inchun

Lin, Rujbin

Van, Fej

Li, Tszyan

Dates

2020-05-29—Published

2016-03-10—Filed